We previously demonstrated that cholesterol deprivation increases endothelial cyclooxygenase-2 (COX-2)-dependent prostacyclin [prostaglandin I2 (PGI2)] production in vitro.Cholesterol directly regulates gene transcription through the sterol response element binding protein (SREBP).In this work, we demonstrate that SREBP directly regulates COX-2 exp
The genus Sidera (Hymenochaetales, Basidiomycota) comprises white-rot, mono- or dimitic fungi with poroid or hydnoid hymenophore.It has a worldwide distribution albeit with fewer species present in the Southern Hemisphere.Although recent studies revealed the existence sweatpants of several new Sidera species, there are still taxonomic inconsistenci
Roberta Lanzillo,1 Raffaele Liuzzi,2 Luca Vallefuoco,3 Marcello Moccia,1 Luca Amato,1 Giovanni Vacca,1 Veria Vacchiano,1 Giuseppe Portella,3 Vincenzo Brescia Morra1 1Neurological Sciences Department, Federico II University, 2Institute of Biostructure and Bioimaging, National Research Council, 3Clinical Pathology Department, Federico II University,
Stroke hemoragik merupakan penyakit yang mengerikan dan hanya 30% pasien bertahan hidup dalam 6 bulan setelah kejadian.Penyebab umum dari perdarahan intrakranial adalah subarachnoid hemorrhage (SAH) dari aneurisma, perdarahan dari arteriovenous malformation (AVM), atau perdarahan intraserebral.Perdarahan intraserebral sering dihubungkan dengan hipe
Molecular dynamics was used in this study to understand the self-healing behavior and mechanism of asphalt.Density, solubility, and mean square displacement parameters were analyzed to confirm the validity of the matrix asphalt model.Molecular simulation software was used to develop a microscopic matrix asphalt self-healing model at the nanoscale.C